Publications

Recent Publications

Huang, D., Bouza, M., Gaul, D. A., Leach, F. E., Amster, I. J., Schroeder, F. C., & Fernández, F. M. "Comparison of High-Resolution Fourier Transform Mass Spectrometry Platforms for Putative Metabolite Annotation". Analytical Chemistry. 2021, 93(36), 12374-12382. DOI:10.1021/acs.analchem.1c02224

Pepi, L. E., Leach, F. E., Klein, D. R., Brodbelt, J. S., & Amster, I. J. "Investigation of the Experimental Parameters of Ultraviolet Photodissociation for the Structural Characterization of Chondroitin Sulfate Glycosaminoglycan Isomers". Journal of the American Society for Mass Spectrometry. 2021, 32(7), 1759-1770. DOI:10.1021/jasms.1c00119

Pepi, L. E., & Amster, I. J. "Electron-activated tandem mass spectrometry analysis of glycosaminoglycans". Current Protocols. 2021, 1, e83. DOI: 10.1002/cpz1.83

Pepi, L. E., & Amster, I. J. “Electron Detachment Dissociation (EDD) and Negative Electron Transfer Dissociation (NETD)”. Advanced Fragmentation Methods in Biomolecular MassSpectrometry, edited by Frederik Lermyte, Royal Society of Chemistry, 2020,  134-170.

Rogals, M. J., Yang, J.-Y., Williams, R. V., Moremen, K. W., Amster, I. J., & Prestegard, J. H. "Sparse isotope labeling for nuclear magnetic resonance (NMR) of glycoproteins using 13C-glucose" Glycobiology. 2020, DOI:10.1093/glycob/cwaa071

Pepi, L. E., Sasiene, Z. J., Mendis, P. M., Jackson, G. P., & Amster, I. J. "Structural Characterization of Sulfated Glycosaminoglycans Using Charge-Transfer Dissociation" Journal of the American Society for Mass Spectrometry. 2020, DOI:10.1021/jasms.0c00252

Pepi, L. E., Sanderson, P., Stickney, M., & Amster, I. J. "Developments in Mass Spectrometry for Glycosaminoglycan Analysis: A Review" Molecular & Cellular Proteomics. 2020, mcp.R120.002267. DOI:10.1074/mcp.R120.002267

Driver, J. A.; Kharchenko, A.; Amster, I. J. "Simulations of nw measurement using multiple detection electrodes in FTICR mass spectrometry" Int. J. Mass spectrom. 2020, 116372 DOI:10.1016/j.ijms.2020.116372

Yu, Y.; Zhang, F.; Renois-Predelus, G.; Amster, I. J.; Linhardt, R. J. "Filter-entrapment enrichment pull-down assay for glycosaminoglycan structural characterization and protein interaction" Carbohydrate Polymers 2020, 116623 DOI:10.1016/j.carbpol.2020.116623

Han, X., Sanderson, P., Nesheiwat, S., Lin, L., Yu, Y., Zhang, F., Amster, I. J., Linhardt, R. J. "Structural analysis of urinary glycosaminoglycans from healthy human subjects" Glycobiology. 2019, 30(3), 143-151. DOI:10.1093/glycob/cwz088

Duan, J.; Pepi, L.; Amster, I. J. "A Scoring Algorithm for the Automated Analysis of Glycosaminoglycan MS/MS Data". Journal of The American Society for Mass Spectrometry 2019, 30 (12), 2692-2703. DOI: 10.1021/jasms.8b06291

Stickney, M.;  Sanderson, P.;  Leach, F. E.;  Zhang, F.;  Linhardt, R. J.; Amster, I. J. "Online capillary zone electrophoresis negative electron transfer dissociation tandem mass spectrometry of glycosaminoglycan mixtures". Int. J. Mass spectrom. 2019, 445, 116209. DOI:10.1016/j.ijms.2019.116209

Williams, R. V.;  Yang, J.-Y.;  Moremen, K. W.;  Amster, I. J.; Prestegard, J. H. "Measurement of residual dipolar couplings in methyl groups via carbon detection". J. Biomol. NMR 2019, 73 (3), 191-198. DOI:10.1007/s10858-019-00245-5.

Stickney, M.;  Xia, Q.; Amster, I. J. "Investigation of electrospray for a capillary electrophoresis–mass spectrometry interface in reverse polarity and negative ion mode". Eur. J. Mass Spectrom. 2019, 25 (1), 157-163. DOI:10.1177/1469066719828192

Duan, J.; Amster, I. J. Chapter 20 - Application of FTMS to the analysis of glycosaminoglycans. In Fundamentals and Applications of Fourier Transform Mass Spectrometry, Kanawati, B.; Schmitt-Kopplin, P., Eds. Elsevier: 2019; pp 623-649. DOI:10.1016/B978-0-12-814013-0.00020-X

Klein, D. R., Leach III, F. E., Amster, I. J., Brodbelt, J. S., "Structural CHaracterization of Glycosaminoglycan Carbohydrates Using Ultraviolet Photodissociation" Anal. Chem. 2019. DOI:10.1021/acs.analchem.9b00521

Moure, M. J.; Eletsky, A.; Gao, Q.; Morris, L. C.; Yang, J.-Y.; Chapla, D.; Zhao, Y.; Zong, C.; Amster, I. J.; Moremen, K. W.; Boons, G.-J.; Prestegard, J. H. "Paramagnetic Tag for Glycosylation Sites in Glycoproteins: Structural Constraints on Heparan Sulfate Binding to Robo1", ACS Chemical Biology 2018. DOI: 10.1021/acschembio.8b00511

Duan, J.; Jonathan Amster, I. "An Automated, High-Throughput Method for Interpreting the Tandem Mass Spectra of Glycosaminoglycans", Journal of The American Society for Mass Spectrometry 2018, 29 (9), 1802-1811. DOI: 10.1007/s13361-018-1969-z

Lu, W.; Zong, C.; Chopra, P.; Pepi, L. E.; Xu, Y.; Amster, I. J.; Liu, J.; Boons, G.-J. "Controlled Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides", Angewandte Chemie International Edition 2018, 57 (19), 5340-5344. DOI:10.1002/anie.201800387

Sanderson, P.; Stickney, M.; Leach, F. E., III; Xia, J.; Yu, Y.; Zhang, F.; Linhardt, R. J.; Amster, I. J. “Heparin/Heparan Sulfate Analysis by Capillary Zone Electrophoresis-Mass Spectrometry”, J. Chromatogr. A 2018, 1545, 75-83. DOI: 10.1016/j.chroma.2018.02.052.

Aebersold, R.; Agar, J. N.; Amster, I. J.; Baker, M.; Bertozzi, C. R.; Costello, C. E.; Cravatt, B. J.; Fenselau, C.; Garcia, B.; Ge, Y.; Gunawardena, J.; Hendrickson, R. C.; Hergenrother, P. J.; Huber, C.; Ivanov, A. R.; Jensen, O.; Jewett, M. C.; Kelleher, N. L.; Kiessling, L. L.; Krogan, N. J.; Larsen, M. R.; Loo, J. A.; Loo, R. R.; Lundberg, E.; MacCoss, M.; Mallick, P.; Mootha, V. K.; Muir, T. W.; Patrie, S. M.; Pesavento, J. J.; Pitteri, S. J.; Rodriguez; H.; Sandoval, W.; Schluter, H.; Sheeley, D. M.; Slavoff, S. A.; Smith, L. M.; Snyder, M. P.; Thomas, P. M.; Uhlen, M.; van der Donk, W. A.; van Eyk, J. E.; Vidal, M.; Walt, D. R.; White, F. M.; Williams, E. R.; Wohlschlager, T.; Wysocki, V. H.; Yates, N. A.; Young, N. L. “How Many Human Proteoforms are There?”, Nat. Chem. Biol. 2018, 14, 206-214. DOI: 10.1038/nchembio.2576.

Driver, J. A.; Nagornov, K. O.; Kozhinov, A. N.; Tsybin, Y. O.; Kharchenko, A.; Amster, I. J., “Multiparticle Simulations of Quadrupolar Ion Detection in an Ion Cyclotron Resonance Cell with Narrow Aperture Detection Electrodes”, J. Am. Soc. Mass Spectrom. 2018, 29, 51-62. DOI: 10.1007/s13361-017-1817-6.

Agyekum, I.; Pepi, L.; Yu, Y.; Li, J.; Yan, L.; Linhardt, R. J.; Chen, S.; Amster, I. J., “Structural Elucidation of Fucosylated Chondroitin Sulfates from Sea Cucumber Using FTICR-MS/MS”, Eur. J. Mass Spectrom. 2018, 24, 157-167. DOI: 10.1177/1469066717731900.

Yu, Y.; Duan, J.; Leach, F. E., III; Toida, T.; Zhang, H.; Zhang, F.; Amster, I. J.; Linhardt, R. J. “Sequencing the Dermatan Sulfate Chain of Porcine Decorin”, J. Am. Soc. Chem. 2017, 139, 16986-16995. DOI: 10.1021/jacs.7b10164.

Leach, F. E., III; Riley, N. M.; Westphall, M. S.; Coon, J. J.; Amster, I. J., “Negative Electron Transfer Dissociation Sequencing of Increasingly Sulfated Glycosaminoglycan Oligosaccharides on an Orbitrap Mass Spectrometer”, J. Am. Soc. Mass Spectrom. 2017, 28, 1844-1854. DOI: 10.1007/s13361-017-1709-9.

Agyekum, I; Zong, C.; Boons, G.-J.; Amster, I. J., “Single Stage MS/MS Analysis of the C-5 Uronic Acid Stereochemistry in Heparan Sulfate Tetrasaccharides Using Electron Detachment Dissociation”, J. Am. Soc. Mass Spectrom. 2017, 28, 1741-1750. DOI: 10.1007/s13361-017-1643-x.

Chen, Y.; Lin, L.; Agyekum, I.; Zhang, X.; St. Ange, K.; Yu, Y.; Liu, J.; Amster, I. J.; Linhardt, R. J., “Structural Analysis of Heparin-Derived 3-O-Sulfated Tetrasaccharides: Antithrombin Binding Site Variants”, J. Pharm. Sci. 2017, 106, 973-981. DOI: 10.1016/j.xphs.2016.11.023.

Lin, L.; Liu, X.; Zhang, F.; Chi, L.; Amster, I. J.; Leach III, F. E.; Xia, Q.; Linhardt, R. J. “Analysis of Heparin Oligosaccharides by Capillary Electrophoresis-Negative-Ion Electrospray Ionization Mass Spectrometry”, Analyt. Bioanalyt. Chem. 2017, 409, 411-420. DOI: 10.1007/s00216-016-9662-1.

Zhao, Y.; Singh, A.; Xu, Y.; Zong, C.; Zhang, F.; Boons, G.-J.; Liu, J.; Linhardt, R. L; Woods, R. J.; Amster, I. J., “Gas-Phase Analysis of the Complex of Fibroblast Growth Factor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study”, J. Am. Soc. Mass Spectrom. 2017, 28, 96-109. DOI: 10.1007/s13361-016-1496-8.